November 28, 2014

Coffee & Copious Co-authorship & Causation & Correlation

Improbable Research - this new study has plenty of something for lots of everyones:

“Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption,” The Coffee and Caffeine Genetics Consortium, M C Cornelis, E M Byrne, T Esko, M A Nalls, A Ganna, N Paynter, K L Monda, N Amin, K Fischer, F Renstrom, J S Ngwa, V Huikari, A Cavadino, I M Nolte, A Teumer, K Yu, P Marques-Vidal, R Rawal, A Manichaikul, M K Wojczynski, J M Vink, J H Zhao, G Burlutsky, J Lahti, V Mikkilä, R N Lemaitre, J Eriksson, S K Musani, T Tanaka, F Geller, J Luan, J Hui, R Mägi, M Dimitriou, M E Garcia, W-K Ho, M J Wright, L M Rose, P K E Magnusson, N L Pedersen, D Couper, B A Oostra, A Hofman, M A Ikram, H W Tiemeier, A G Uitterlinden, F J A van Rooij, I Barroso, I Johansson, L Xue, M Kaakinen, L Milani, C Power, H Snieder, R P Stolk, S E Baumeister, R Biffar, F Gu, F Bastardot, Z Kutalik, D R Jacobs Jr, N G Forouhi, E Mihailov, L Lind, C Lindgren, K Michaëlsson, A Morris, M Jensen, K-T Khaw, R N Luben, J J Wang, S Männistö, M-M Perälä, M Kähönen, T Lehtimäki, J Viikari, D Mozaffarian, K Mukamal, B M Psaty, A Döring, A C Heath, G W Montgomery, N Dahmen, T Carithers, K L Tucker, L Ferrucci, H A Boyd, M Melbye, J L Treur, D Mellström, J J Hottenga, I Prokopenko, A Tönjes, P Deloukas, S Kanoni, M Lorentzon, D K Houston, Y Liu, J Danesh, A Rasheed, M A Mason, A B Zonderman, L Franke, B S Kristal, International Parkinson’s Disease Genomics Consortium (IPDGC), North American Brain Expression Consortium (NABEC), UK Brain Expression Consortium (UKBEC), J Karjalainen, D R Reed, H-J Westra, M K Evans, D Saleheen, T B Harris, G Dedoussis, G Curhan, M Stumvoll, J Beilby, L R Pasquale, B Feenstra, S Bandinelli, J M Ordovas, A T Chan, U Peters, C Ohlsson, C Gieger, N G Martin, M Waldenberger, D S Siscovick, O Raitakari, J G Eriksson, P Mitchell, D J Hunter, P Kraft, E B Rimm, D I Boomsma, I B Borecki, R J F Loos, N J Wareham, P Vollenweider, N Caporaso, H J Grabe, M L Neuhouser, wolffenbB H R Wolffenbuttel [pictured here], F B Hu, E Hyppönen, M-R Järvelin, L A Cupples, P W Franks, P M Ridker, C M van Duijn, G Heiss, A Metspalu, K E North, E Ingelsson, J A Nettleton, R M van Dam and D I Chasman, Molecular Psychiatry, epub October 7, 2014.

“We conducted a genome-wide (GW) meta-analysis of predominately regular-type coffee consumption (cups per day) among up to 91 462 coffee consumers of European ancestry with top single-nucleotide polymorphisms (SNPs) followed-up in ~30 062 and 7964 coffee consumers of European and African-American ancestry, respectively. Studies from both stages were combined in a trans-ethnic meta-analysis. Confirmed loci were examined for putative functional and biological relevance.”

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